A Comprehensive Health Effects Assessment of the Use of Sanitizers and Disinfectants during COVID-19 Pandemic: A Global Survey (preprint)

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are critical concerns about their adverse effects on human health. This study aims to assess the health effects of sanitizers and disinfectants on a global scale. A total of 91056 participants from 154 countries participated in this cross-sectional study through an electronic questionnaire. Results implied that detergents (67%), alcohol-based materials (56%), and chlorinated compounds (32%) were the most commonly used types of sanitizers and disinfectants. Most frequently reported health issues include skin complications 48.8% and respiratory complications 29.8%. The Chi-square test showed a significant association between chlorinated compounds with all possible health complications under investigation (p-value < 0.001). Examination of risk factors based on multivariate regression analysis showed that alcohols-based materials were associated with skin complications (OR, 1.98; 95%CI, 1.87–2.09), per-chlorine was associated with eye complications (OR, 1.83; 95%CI, 1.74–1.93), and highly likely with itching and throat irritation (OR, 2.00; 95%CI, 1.90–2.11). Furthermore, formaldehyde was associated with a higher prevalence of neurological complications (OR, 2.17; 95%CI, 1.92–2.44). The findings of the current study suggest that health authorities need to implement more awareness programs about the side effects of using sanitizers and disinfectants during viral epidemics.

Determinants of psychological distress during the COVID-19 pandemic and the lockdown measures: a nationwide on-line survey in Greece and Cyprus (preprint)

Abstract A limited number of studies have investigated the distress during the COVID-19 pandemic and the lockdown measures in the general population. We studied psychological distress during the COVID-19 pandemic and the lockdown measures in the general population in Greece and Cyprus. Also, we investigated several demographic, clinical and job characteristics of the participants as possible determinants of distress. Data collection was performed during lockdown measures in Greece and Cyprus (from April 21st to May 4th 2020). All participants provided informed consent to participate in the study. We used the Impact of Event Scale-Revised (IES-R) to measure the psychological distress in response to the COVID-19 pandemic and lockdown measures. Seventeen point four percent of the participants had overall IES-R score from 24 to 32 indicating that posttraumatic stress disorder (PTSD) is a clinical concern, while 33.5% had overall IES-R score >32 indicating that PTSD is a probable diagnosis. Females, Cyprus residents, participants that live with elderly people or patients with a chronic disease in home, participants with a mental health disease or/and chronic disease, participants under pharmaceutical treatment, participants that lost their work due to the pandemic and participants that work in hospital experienced greater distress. Also, increased age and decreased educational level was associated with increased distress. Findings suggest that our sample experienced great distress and this distress was affected by several demographic, clinical and job characteristics. Appropriate interventions should be established in order to support psychologically high risk groups and decrease their distress. Keywords: distress, COVID-19, posttraumatic stress disorder, cross-sectional study, on-line survey, public health